Citi analysts are expecting Citigroup Inc. (NYSE:C) to report a $4.3 billion quarterly loss for the second quarter, the biggest drop in three years.

Citi analysts said in a note on Tuesday that the company has been underperforming for the past several quarters due to several factors including higher drug costs, weaker demand for drugs and weak demand for CitiCare products, which provide health insurance for people with pre-existing conditions.

Citigroup shares fell 6.3% in early trading on Tuesday.

Citi shares rose 3.8% in after-hours trading on Monday.