SANTA CRUZ, Calif.

— Lexicon Pharmaceutical is going to be up $10.75 a share, to $33.25.

That’s the stock’s best opening since June 2011.

And it’s still way down from the peak of $49 a share a year ago, when Lexicon was trading at more than $100 a share.

The company said Monday that its stock is up more than 60% since the start of the year.

At the close Monday, Lexicon is up $6.50, or 5.2%, to $32.80.

Lexicons shares have gone up nearly 1,000% since they hit a high of $30.83 in December 2008, before the financial crisis.